Recently, Fuji Silysia of Japan obtained CDMF of exipient and published, the registration number is F20180001494, F20180001495 and F20180001496, respectively, through the CDE official website "raw material medicine, pharmaceutical accessories and drug packaging material registration information publicity" entry query
Fuji Silysia of Japan is prepared by sol-gel method. The preparation process is to fully mix raw materials in the liquid phase, and then hydrolyze, condensation or polymerization and other chemical reactions to form a stable transparent sol system. Then the sol was gelated to obtain the coarse gel with 3d mesh structure.
Silica products were obtained by washing, drying and packing the crude products. This special network structure gives the gel a high specific surface area, which can reach 300-700m2/g. Fuji Silysia of Japan names the product according to different specific surface area.